Ovarian follicular development in the pregnant rat.
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概要
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The size distribution of ovarian follicles was examined histologically duringpregnancy in the Wistar rats. The number and size distribution of healthy and atretic follicles larger than 350 μm in diameter were determined for each day of pregnancy. Throughout pregnancy and day of parturition, the mean number of healthy follicles larger than 350 μm per ovary ranged from 17.6 to 32.6 and the number was maximum 32.6 on day 2 (day 1 of pregnancy = day sperm positive). Higher number (6.8-8.1) of healthy follicles larger than 550 μm per ovary were observed on days 7-9 and 22, while the number decreased markedly on days 14-21. There was an inverse relation between the number distribution of healthy follicles of 350-549 μm and that of healthy follicles larger than 550 μm. The mean number of atretic follicles larger than 350 μm per ovary ranged from 5.0 to 13.7. These results indicate that the development of small follicles to large follicles occurs mainly on about days 7-9 and 22 of pregnancy.
- 日本繁殖生物学会の論文
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