Luteotrophic effect of deciduoma in rats.
スポンサーリンク
概要
- 論文の詳細を見る
Luteotrophic effect of decidual tissue was examined in Holtzman rats by observing length ofpseudopregnancy or by measuring progesterone and 20α-hydroxyprengn-4-en-3-one (20a-OHP) in>ovarian effluent blood plasma.<BR>The length of pseudopregnancy was significantly longer in traumatized rats than in hysterecto->mized-pseudopregnant animals (23.0±0.97 υs 19.3±0.93; mean±SE). When deciduomectomy (removalof uterus bearing deciduomata) was performed on days 7 and 9, pseudopregnancy lasted only 17.4±0.92 and 19.4±1.25 days, respectively, which were similar to the value observed for hysterecto-mized-pseudopregnant animals.<BR>Progestin levels in both the traumatized and the hysterectomized-pseudopregnant rats were>similar to each other on day 7. An increase in progestin levels, however, occured in traumatizedanimals from days 7 to 9 of pseudopregnancy and the levels of progesterone and 20α-OHP on day >9 were significantly higher in the animals with deciduomata by 1.6- and 2.2-fold, respectively, ascompared with those in hysterectomized-pseudopregnant ones. Following deciduomectomy on day 7, the increase in each progestin level from days 7 to 9 was not seen. On the other hand, hypophy->sectomy performed on day 7 in traumatized rats resulted in a dramatic decrease in progesteronelevel coincident with an increase in 20α-OHP level on day 9 without changing total progestin level(sum of progesterone and 20α-OHP).<BR>Thus, the luteotrophic action of decidual tissue was suggested by the prolongation of pseudo-pregnancy and the elevation of ovarian progesterone secretion, and it was not seen in the absence of pituitary.
- 日本繁殖生物学会の論文
日本繁殖生物学会 | 論文
- 近交系Hatanoラットに認められた春機発動時期および血漿中ホルモン濃度の系統差
- ラット卵子の自発的第一卵割に及ぼすCa2+/Mg2+不含培養液の影響
- 体外受精由来ウシ胚盤胞のガラス化保存においてバイオプシー後の培養時間が融解後の生存性に与える影響
- ブタ生体回収由来ガラス化胚の生存性の改善
- 卵細胞質内注入法を用いた牛の核移植