Embryological changes of implanted eggs in superovulated mice

概要

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Embryological changes of implanted eggs in mice treated with superovulation treatment (S. O.), S. O. + progesterone, and S. O. + prolactin were observed using the mice on the 7th day after conception. The results obtained were as follows: 1) Normal developmental stage of implanted eggs was that of egg cylinder. Retarded eggs such as small egg cylinder, early egg cylinder and later blastocyst were also found all through the experimental groups. 2) The retarded eggs appeared more frequently in mice with S.O. treatment, as compared with naturally pregnant mice. Among treated mice, the mice treated with S. O. + prolactin showed the least number of retarded eggs, suggesting some good effect of prolactin on the egg development. 3) It was not necessarily comfirmed that the more the implanted eggs, the more the retarded ones. 4) Retarded eggs were found either distributed in both uteri, or only in one of them. They were frequently found at the region near the ovary or near the vagina, more near the ovary than vagina. 5) Development of the decidual membrane in the implanted uterus was good on the whole. On the contrary. it hardly or not at all develoned in the implantation-failing uterus.
日本繁殖生物学会の論文