Immunohistochemical localization of .ALPHA.-fetoprotein in the bovine placentome.
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概要
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The localization of α-fetoprotein (AFP) in the bovine placentome was shown by the immunohistochemical method using Avidin-Biotin Peroxidase Complex (ABC). The intense staining specific to AFP was recognized in the fetal part of the placentome, especially capillary of the villus and wall of blood vessel in the allanto-chorion. Trophoblastic cells such as binucleate giant and mononucleate cells were negative for AFP. In contrast to the fetal parts of the placentome, no specific staining to AFP was found in the maternal component such as the cryptal epithelia, blood vessels in the maternal septa and the pedicle of the placentome. The localization of AFP was restricted in the fetal component of the placentome. Therefore, it is suggested that AFP may not transfer from fetus to the maternal blood circulation across the placental barrier.
- 日本繁殖生物学会の論文
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