Identification of a reactive metabolite of the mutagen, 2-amino-3-methylimidazolo(4,5-f)quinoline.
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概要
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A reactive major metabolite of the mutagen, 2-amino-3-methylimidazolo [4, 5-f]-quinoline (IQ), by rat liver microsomes was 2-hydroxyamino-3-methylimidazolo [4, 5-f]-quinoline (N-OH-IQ). The synthesis and reaction with DNA of N-OH-IQ were discussed.
- 社団法人 日本薬学会の論文
社団法人 日本薬学会 | 論文
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