Mild Deprotection of Methylene Acetals in Combination with Trimethylsilyl Triflate–2,2′-Bipyridyl

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概要

• 論文の詳細を見る

• The facile deprotection of methylene acetal protection of diols under mild conditions is established. The combination of trimethylsilyl triflate (TMSOTf) and 2,2′-bipyridyl followed by a weakly acidic hydrolysis was effective and the substrates having acid sensitive functional groups can be tolerated under the stated conditions. The selective deprotection between methylene acetal and benzophenone ketal was achieved.

• 社団法人 日本薬学会の論文

著者

• FUJIOKA Hiromichi

  Graduate School of Pharmaceutical Sciences, Osaka University

• Senami Kento

  Graduate School of Pharmaceutical Sciences, Osaka University

• Kubo Ozora

  Graduate School of Pharmaceutical Sciences, Osaka University

• Yahata Kenzo

  Graduate School of Pharmaceutical Sciences, Osaka University

• Minamitsuji Yutaka

  Graduate School of Pharmaceutical Sciences, Osaka University

• Maegawa Tomohiro

  Graduate School of Pharmaceutical Sciences, Osaka University

• Maegawa Tomohiro

  Graduate School Of Pharmaceutical Sciences Osaka University

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