Studies on Decomposition and Stabilization of Drugs in Solution. XIX. Critical Micelle Concentration of Acylcholine
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Critical micelle concentrations (CMC) of acylcholines were measured by surface tension, colorimetry of Sky blue FF, fluorophotometry of Eosin and solubilization of Sudan III. Formation of micelle was not observed on acetylcholine chloride, propionylcholine iodide, butyrylcholine iodide and hexanoylcholine iodide, but observed on octanoylcholine iodide, decanoylcholine iodide, dodecanoylcholine iodide and hexadecanoylcholine iodide. Relationship between log CMC of octanoylcholine iodide, decanoylcholine iodide and dodecanoylcholine iodide by solubilization of Sudan III at 45° and the number (N) of carbon atoms in the hydrocarbon chain was written in the following manner. log CMC(M)=1.040-0.295n
- 社団法人 日本薬学会の論文
社団法人 日本薬学会 | 論文
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