Papanicolaou smears in patients with endometrial carcinoma
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概要
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<B><I>Objective</I>:</B> To correlate findings of cervical cytology and poor prognostic factors in patients with endometrial cancer because the spread of endometrial cancer may be predictable by cervical cytology.<BR><B><I>Study Design</I>:</B> Subjects were 55 women with endometrial cancer who underwent cervical cytology before surgical staging. We analyzed the relationship between Papanicolaou smear findings by Bethesda system 2001 and poor prognostic factors of endometrial cancer.<BR><B><I>Results</I>:</B> Cervical cytology was normal in 22 patients, AGUS in 6, AGUS-FN in 8, and adenocarcinoma in 19. Patients with a cytologic diagnosis of adenocarcinoma were significantly more likely to have invasion in more than half of the myometrium (78.9 vs 27.3%), FIGO stage II-IV (63.1 vs 4.5%), and nonendometrioid histology (21.1 vs 0.0%) than those with normal cytology. No association was found between findings of cervical cytology and tumor grade.<BR><B><I>Conclusion</I>:</B> When cytologic diagnosis in endometrial cancer indicates adenocarcinoma, there is a high probability that the patient has a high-risk neoplasm with poor prognosis.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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