T-cell rich B-cell large cell lymphoma.
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概要
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Two cases of T-cell rich B-cell large cell lymphoma are described in which the cytology and initial histology suggested a diagnosis of T-cell Lennert's lymphoma. Patients were a male of ages 74 years and a female of ages 58 years. Imprint cytology of biopsied lymph nodes showed many small lymphocytes accounted for 65% to 70% and sparse large lymphoid cells for 20% to 30%. Medium-sized prolymphocytes, epithelioid cells, plasmacytoid cells and eosinophils were also observed. Flow cytometry for surface antigens of cells from lymph nodes indicated many CD 2 and CD 3 positive T-cells. However, immunohistochemistry on paraffin sections confirmed that many small and medium-sized cells were UCHL 1 and MT 1 positive T-cells and small population of large cells were L 26 positive B-cells. Then the diagnosis was changed to T-cell rich B-cell largecell lymphoma. The differential diagnosis in cytology from reactive changes, Lennert's lymphoma and related diseases was discussed.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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