Two cases of apocrine sweat gland carcinoma of axilla.
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概要
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<B><I>Background</I>:</B> Apocrine sweat gland carcinoma is a rare lesion. and its cytological features have not been adequately reported. Recently, an immunohistochemical method recently for the diagnosis of this rare lesion has become available. We experienced two cases of apocrine sweat gland carcinoma arising in the axillary region.<BR><B><I>Cases</I>:</B> Case 1 was a 49-year-old male who had undergone a tumorectomy in his left axilla 5 years prior to the recurrence. Fine-needle aspiration revealed isolated or small clusters of tumor cells with thickened cytoplasm. peripherally located nuclei, and decapitation secretion. Histologically, solid proliferated tumor cells with broad and eosinophilic cytoplasm, decapitaion secretiton and diastase-resistant PAS positive granules were observed. The tumor cells were positivie for GCDFP-15. Case 2 was a 53-year-old male with a 15-year history of a left axillary mass. Scratch cytology of a lymph node during a tumorectomy showed sheet clusters of rather large tumor cells with broad cytoplasm. peripherally located nuclei with distinct nucleoli. orange C-positive coarse granules, and decapitaion secretion. Histologically, the tumor consisted of mainly tubular structures that had invaded the subcutaneous tissue. The tumor cells with the eosinophilic cytoplasm and decapitation secretion were positive for GCDFP-15.<BR><B><I>Conclusion</I>:</B> Apocrine sweat gland carcinoma must be differentiated from an apocrine carcinoma originated from accessary breast and metastatic adenocarcinoma. Cytologically, this lesion (including metastatic lesions) exhibits features that are specific to apocrine sweat glands, enabling an accurate diagnosis.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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