AFP production by sex cord stromal tumor with annular tubules.
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概要
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<B><I>Background</I>:</B> Sex cord tumor with annular tubules (SCTAT) is a rare entity, with only 15 cases reported in Japan. We report such a case, and its cytological and immunohistochemical findings.<BR><B><I>Case</I>:</B> A 63-year-old gravida 2, para 2 woman was found to have an intrapelvic mass by ultrasonography on a routine medical examination. She had no signs of Peutz-Jeghers syndrome. A right oophorectomy was performed and the right ovary was occupied by a 9×7×6cm multilocular cystic tumor. Many epithelial clusters in stamp and squashed cytological specimens were obtained from the thickened cystic wall. Epithelial clusters formed tubular and lobular structures. The majority of epithelial cells had clear cytoplasm with PAS-positive granules. A few epithelial cells had cytoplasmic alcianophilic mucin. They were also immunoreactive for CA19-9 and CEA, and were considered to be a heterologous element of intestinal epithelial cells. The majority of epithelial cells was negative for CEA or CA19-9, but positive for AFP.<BR><B><I>Conclusion</I>:</B> Since the association of heterologous elements and the expression of AFP are frequently seen in Sertoli-Leydig cell tumor, this case was considered to be related to Sertoli-Leydig cell tumor.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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