A case of heterologous carcinosarcoma of the uterus with a clear-cell adenocarcinoma component.
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<B><I>Background</I>:</B> Carcinosarcoma of the uterus with a clearcell adenocarcinoma component is an uncommon malignancy. We present a case of heterologous carcinosarcoma of the uterus with such a component.<BR><B><I>Case</I>:</B> Preoperative cytology in a 77-year-old woman suffering from vaginal bleeding showed small clusters originating from endometrioid adenocarcinoma, and cauliflower-like clusters composed of cells with abundant clear cytoplasm, fine granular chromatin, and prominent nucleoli, derived from clear cell adenocarcinoma. Cervical and cervical canal specimens showed isolated large cells intermingled with naked nuclei originating from a nonepithelial tumor. Biopsy specimens from the endometrium and cervix showed no sarcomatous components. Histological examination of the resected specimen showed endometrioid adenocarcinoma and clear-cell adenocarcinoma as epithelial components and stromal sarcoma and chondrosarcoma as nonepithelial components. The pathologic diagnosis was of heterologous carcinosarcoma with clear-cell adenocarcinoma component.<BR><B><I>Conclusion</I>:</B> Prognosis for patients with such tumors is considered worse than that for ordinary endometrioid adenocarcinoma. When an ordinary endometrioid adenocarcinoma component is found in the uterine smear specimen, other atypical epithelial and nonepithelial cells should not be thoroughly checked for.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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