A feature of adenoma malignum of the uterine cervix in mucin stains.
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概要
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The present study was undertaken to explore the characteristics of yellow or yellowish brown mucin by Pap. staining in Adenoma malignum. A histochemical study on this tumor has revealed that the mucus of this tumor was different in nature from the normal cervical glands and well differentiated adenocarcinoma of the cervix.<BR>Histochemical staining-(periodic acid schiff, PAS; alcian blue, AB; high iron diamine-alcian blue, HID-AB) was done using paraffin-embedded sections from 5 cases of adenoma malignum, 8 cases of well differentiated adenocar cinoma and 21 cases of normal cervix. A positive PAS reaction was observed in all normal controls, while all patient samples were positive but the intensity was weaker than the controls in adenoma malignum. A positive AB reaction was observed in all normal controls, but not in four cases of adenoma malignum and one case showed only a weak positive reaction. In HID-AB staining, both sulphomucin and sialomucin were predominant in well differentiated adenocarcinoma but both were negative in adenoma malignum, which is supposed to be neutral mucin on histochemical staining.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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