Morphology of myoepithelial cells seen in pleomorphic adenoma of the salivary gland.
スポンサーリンク
概要
- 論文の詳細を見る
<B><I>Objective</I>:</B> Pleomorphic adenoma of the salivary gland is a benign tumor composed of epithelial, myoepithelial and mesenchymal elements. The myoepithelial cells show a variety of shapes, such as spindle, stellate, epitheliold and plasmacytoid (hyaline cells) or clear cytoplasm. To evaluate the morphology of the myoepthelial cells seen in pleomorphic adenoma, we examined seven cases of pleomorphic adenoma by immunocytochemistry.<BR><B><I>Study design</I>:</B> The study group consisted of seven samples of pleomorphic adenoma obtained by fine needle aspiration cytology in Kurashiki Central Hospital. Immunocytochemical staining for vimentin, alpha-smooth muscle actin (α-SMA), S-100 protein, keratin 8, carcinoembryonic antigen (CEA) and epithelial membrane antigen (EMA) was performed on Papanicolaou-stained smears using the streptavidin-biotin method. We indentified vimentin-, α-SMA-, S-100 protein-and keratin 8-positive and CEA and EMA-negative cells as myoepithelial cells.<BR><B><I>Results</I>:</B> Myoeithelial cells were subdivided into five types: plasmacytoid, lymphoid, tail, stellate and spindle cells. All types were observed in each case. Plasmacytoid cells were individually scattered. Lymphoid cells were located around or above cell clusters. Tail cells appeared at the periphery of cell clusters or around them. Stellate cells were present in mucoid material. Spindle cells formed bundles or were individually scattered.<BR><B><I>Conclusion</I>:</B> Our results indicate that myoepithelial cells seen in pleomorphic adenoma morphologically showed five types, and all types were present in each case.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
- Cytology of Carcinoid of Digestive Organs
- T-cell rich B-cell large cell lymphoma.
- Symposium on borderline lesions. 1. Aspiration cytology of lymph nodes with special reference to malignant lymphoma.
- A case of endometrioid adenocarcinoma, so-called secretory variant.
- Significant factors influencing the accuracy of PTCD bile cytology for bile duct lesions.