Aspiration cytologic findings of infiltrating lobular carcinoma of the lactating breasts-Report of a case.
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概要
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<B><I>Background</I></B>: Infiltrating lobular carcinoma of both breasts in a 35-year-old woman, who was breast feeding her 6-month-old baby is described.<BR><B><I>Case</I></B>: The patient complained of progressively increasing swelling and pain of the bilateral breasts. An aspiration cytologic study on admission indicated lactating adenoma. A week later a cytologic study was repeated, based on suspicion of an inflammatory carcinoma. Simultaneous needle biopsy and systemic examinations revealed bilateral infiltrating lobular carcinoma of the breasts with widespread hepatic metastasis. The initial and repeat cytologic findings were essentially the same and very similar to those of an ordinary lactating adenoma, showing small varyious shaped clusters of tumor cells with focal mild piles and loose cohesion. The cells had abundant foamy cytoplasms and eccentric small round nuclei with enlarged nucleoli and fine chromatin. Furthermore, frequent mild nuclear size variation and perinucleolar halo were seen. The isolated scattered tumor cells had varying amounts of cytoplasm, and none were naked. A few cell clusters of ductal origin were found, but there was no atypia. Histologic findings were consistent with infiltrating tumors composed of sheets and cords of polygonal clear foamy cells and edematous fibrous stroma.<BR><B><I>Conclusion</I>:</B> This is an unusual case and, to our knowledge, the first cytologic report of infiltrating lobular carcinoma-arising in the lactating breast in the literature.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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