Cytologic features of saromatoid salivary duct carcinoma ex pleomorphic adenoma of the parotid gland.
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概要
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<I><B>Background</B></I>: Salivary duct carcinoma (SDC) is a rare high grade carcinoma arising from the salivary glands. Approximately 20% of SDCs are associated with pleomorphic adenoma. Sarcomatoid SDC has not been described. It is important to clarify the cytologic features of SDC to differentiate it from other salivary gland carcinomas because of the different biologic behavior.<BR><I><B>Case</B></I>: A 67-year-old Japanese woman was admitted because of a left parotid mass. An aspiration biopsy cytology specimen suggested malignant myoepithelioma. Cytologic examination of the imprint specimen of the resected tumor revealed clusters of overlapping cells with a focal palisaded arrangement as well as scattered, isolated round or spindle -shaped cells. Necrosis was pronounced. Histologically, the tumor was diagnosed as sarcomatoid SDC ex pleomorphic adenoma. We interpreted the aggregated cells as those of typical SDC and the isolated cells as those of the sarcomatoid element.<BR><B><I>Conclusion</I>:</B> Cytologic features of SDC were clusters of overlapping atypical cells showing a palisaded arrangement with necrosis. On the other hand, when isolated, spindleshaped atypical cells are identified, not only malignant myoepithelioma but other carcinomas including sarcomatoid SDC might be considered.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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