Intraoperative rapid imprint cytologic examination of surgical margin in breast cancer conserving surgery.
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概要
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In order to perform reasonable breast conserving surgery for breast cancer, intraoperative rapid imprint cytologic examination was employed to diagnose the extent of cancer spread at the surgical margin. Thirty-three patients underwent breast conserving surgery in our hospital from April 1993 to June 1996. The following conclusions were derived:<BR>1. Sensitivity, specificity and accuracy were 100%, 90.7% and 92.4% respectively.<BR>2. Most true positives revealed non-invasive carcinoma, while false positives were ductal hyperplasia. The differential points in both cases were (1) Appearance types and numbers of cells in the background.(2) Cohesion of epithelial cell clusters and presence of myoepithelial cells.(3) Nuclear form and various sizes of epithelial cells and periglandular nuclear forms.(4) Hyperchromatin and prominent nucleoli.<BR>3. The direction of intraductal cancer spread from the tumor margin was predominanthy toward the nipple side (15.3mm in average length), followed by the superior lateral side (6.4mm), inferior lateral side (6.2mm) and distal side (5.0mm).
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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