A case of poorly differentiated endometrial sarcoma. On the imprint cytology.:on the imprint cytology

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A case of poorly differentiated endometrial sarcoma is reported with reference to the cytologic findings. The paitent, a 52-year-old woman, visited our hospital because of brownish vaginal discharge, hypermenorrhea and lumbago. A uterine tumor of the size of a child's head was disclosed, and total hysterectomy with bilateral salpingo-oophorectomy was performed. The uterine cavity was filled with a polypoid mass originating from the endometrium and involving the myometrium, the cervix and the right parametrium. The histology of the tumor mass demonstrated a poorly differentiated endometrial sarcoma thought to be a monophasic variant of malignant mixed Mtillerian tumor. On the imprint cytology from the tumor, numerous atypical cells were observed diffusely. Their nuclei showed anisonucleosis, an irregular shape, pleomorphism and hyperchromasia with a fine granular distribution, and had one or two nucleoli and thin nuclear rims. Many mitotic figures were seen and multinucleated giant cells or bizarre cells were also observed. The cytoplasms were faintly stained and the boundaries were indistinct. The cytologic findings were suggestive of an anaplastic type of non-epithelial malignant tumor.
特定非営利活動法人日本臨床細胞学会の論文