Significance of the cell block method in combination with cytology in mass screening for endometrial cancer.
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概要
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To improve the diagnostic accuracy of endometrial cytology, the cell block method was used in combination with cytology for endometrial cancer screening in cytological specimens. The specimens were obtained using a brush from 87 patients who visited the Gynecology Clinic of Aichi Medical University Hospital complaining of irregular vaginal bleeding or requesting cytological examinations.<BR>Based on endometrial cytological evaluation, the 87 subjects consisted of 78 cases considered negative, 3 cases with suspicious positive lesions and 6 cases with positive lesions. Evaluation with the cell block method served to classify them into 62 cases with no malignancies, one with atypical hyperplasia, 8 with adenocarcinomas, and 16 with sampling errors. In 67 (94.4%) of 71 cases, excluding those with sampling errors, the cytology results agreed with those obtained by the cell block method. However, 2 cases judged to be suspicious positive by cytology were diagnosed correctly as adenocarcinoma by the cell block method; and one case judged to be negative by cytology was diagnosed as atypical hyperplasia with the cell block method. Eight (88.9%) of 9 cases of endometrial adenocarcinoma diagnosed histologically with specimens obtained by endometrial biopsy curettage proved to be adenocarcinoma by the cell block method, although 6 cases (66.7%) among them were also positive by cytology. Another case was negative in both cytology and the cell block method.<BR>These results led us to conclude that the cell block method, in combination with endometrial cytology, improved the diagnostic accuracy of mass screening for endometrial cancer.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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