A case report of malignant thymoma with distant metastases.
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The patient was a 78-year-old man. He was first found to have a right cluneal tumor. A chest roentgenogram confi rmed a large anterior mediastinal mass.<BR>The tumor cells consisted of epithelial cells. These cells appeared collectively or as isolated cells. The cells were small with round or spindle-form nuclei, and the cytoplasm was relatively scant. The nuclei were finely granular and had evenly distributed chromatin and indistinct nucleoli. Mitotic figures were rarely present.<BR>At autopsy, a firm mass was observed within the anterior mediastinum. The tumor measured 15×10×4cm in its greatest dimensions and hemorrhage and necrosis of the central area were observed. Tumor invasion was not present in the pleura, pericardium, diaphragm, or lung, although distant metastases were found in the left and right lung, liver, left clavicle, left sixth costa, and right ilium.<BR>The tumor was composed predominantly of epithelial type cells with hemorrhage and necrosis. Cytologically, part of the tumor cells had a coarse granular pattern of the nuclei. These characteristics seemed to suggest the malignant behavior of the tumor.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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