Cytologic diagnosis of the dysfunctional uterine bleeding and its clinical significance.
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Endometrial scraping for cytologic examination has not been frequently applied to diagnose dysfunctional uterine bleeding. In this report, we attempted to determine whether this examination could reflect endometrial features of dysfunctional uterine bleeding, and studied the clinical significance of this examination.<BR>Cases with proliferative endometrium and endometrial hyperplasia represented 92% of 25 cases of the proliferative type. Cases with secretory endometrium represented 93% of 14 cases of the secretory type. Cases with irregular shedding, proliferative endometrium and endometrial hyperplasia, and secretory endometrium were observed in 25, 50% and 25%, respectively, among 20 cases of mixed type. Cases having both extensive gland formation of gland cells and features of fasciculus agglutination of stromal cells were observed in 87% of cases of glandular cystic hyperplasia.<BR>In histological diagnosis, endometrial scraping for cytologic examination can rapidly distinguish ovulatory bleeding of the secretory type and generally indicates good prognosis, while anovulatory proliferative type bleeding tends to replase and has a comparatively poor prognosis. Therefore, the examination could be useful in terms of hormone therapy for cases with dysfunctional uterine bleeding. Furthermore, we considered it possible to anticipate endometrial hyperplasia from quantitative or morphologic changes of glandular cells and stromal cells.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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