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Carcinoembryonic antigen (CEA) was studied by the indirect immunoperoxidase technique in 10% formalinfi xed paraffin-embedded tissue specimens from 61 patients and 95% ethanolfixed smears from 26 patients with gynecologic malignancies. The tissue specimens included cervical adenocarcinoma (26 cases), cervical adenosquamous cell carcinoma (10 cases), cervical squamous cell carcinoma (7 cases), endometrial adenocarcinoma (16cases) and ovarian adenocarcinoma (2 cases). The cytological specimens included corvical adenocarcinoma (5cases), cervical adenosquamous cell carcinoma (2 cases), cervical squamous cell carcinoma (7 cases), endometrial adenocarcinoma (10 cases) and ovarian adenocarcinoma (2 cases). In tissue specimens, positive CEA staining was seen 7 of 7 squamous cell carcinomas (100%), 9 of 10 adenosquamous cell carcinomas (90%), 21 of 26 cervical adenocarcinomas (80. 8%), 2 of 2 ovarian adenocarcinomas (100%) and 8 of 16 endometrial adenocarcinomas (50%). In cytological specimens, positive CEA staining was seen all of smears except one of the endometrial adenocarcinoma.<BR>In tissue specimens, positive area was diffuse in cervical carcinomas. Cytoplasmic membrane or secretory granules were stained diffusely. As for endometrial carcinomas positive area was localized in acanthomatous or metaplastic portion. Cytological specimens of cervical carcinomas were positive CEA staining, and 9 of 10 positive CEA staining were observed in endometrial carcinomas as same as cervical carcinomas.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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