Scanning Electron Microscopic Studies on Precance rous and Cancerous Lesions of Cervix Uteri
スポンサーリンク
概要
- 論文の詳細を見る
Scanning electron microscopic observations were performed to study the ultrastructure of the surface of precancerous lesions and invasive cancers of the uterine cervix.Specimens were collected from patients who visited the Gynecologic Cancer Clinic of Keio University Hospital.<BR>1.Normal squamous epithelium: Thin polygonal cells were arranged regularly in the shape of pavement and the nuclear excrescences were observed in the center of the cells.Numerous, short and irregular villous processes were seen on the surface, and irregular runs of small grooves on the back side of the cells.The surface of the underlying cells was covered by a network of cytoplasmic microridges.<BR>2.Metaplastic epithelium: It was composed of round to elipsoid shaped cells varying slightly in size.The surface was covered by short, rounded, villiform proje ctions.The intercellular spaces were dilated, and well developed intercellular bridges noted.<BR>3.Dysplasia: Cells with increased nucleocytoplasmic ratio were arranged irregularly and the overlapping of cells was noted.The villiform projections of most cells were shorter, and had rounded tips, as compared with those of normal squamous epithelium.<BR>4.Carcinoma in situ: Relatively uniform and round cells were packed together, exhibiting a somewhat monotonous picture.However, the arrangement of the cells was irregular, and the overlapping of the cells was apparent.The microvilli on the surface of the cells were much shorter in size and rounder in shape, and were almost granular.<BR>5.Early invasive carcinoma: It was mainly composed of round cells as seen in carcinoma in situ, but mixed with those cells were differentiated malignant cells having slender cytoplasmic processes.<BR>6.Invasive carcinoma: Cells of markedly irregular sizes and irregular shapes were seen overlapping in the way of house tiles.Various kinds of bizarreshaped cells were observed on the surface of the tumor. The surface of most cells was rather granular.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
- Cytology of Carcinoid of Digestive Organs
- T-cell rich B-cell large cell lymphoma.
- Symposium on borderline lesions. 1. Aspiration cytology of lymph nodes with special reference to malignant lymphoma.
- A case of endometrioid adenocarcinoma, so-called secretory variant.
- Significant factors influencing the accuracy of PTCD bile cytology for bile duct lesions.