Tofu (soybean curd) Prevents Life-style Related Diseases in Rat Models of Hypertension and Diabetes
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概要
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Life-style related diseases are caused by a combination of genetic and environmental factors, including diet.The purpose of this study was to examine whether Tofu (soybean curd) prevents life-style related diseases.Thirty-four spontaneously hypertensive rats (SHR) and thiry-five diabetic rats (GK), 3-week-old males just after weaning, were used in the experiment.The animals in each strain were randomly divided into three groups of high sample diet (High), low sample diet (Low), and no sample diet (Control). The High and Low groups were fed a powdered commercial diet (CE-2, Japan Clea Co., Ltd.) containing 2.0% and 0.5% Tofu, respectively.The Control group was fed only a powdered commercial diet.The rats were fed these diets for 30 weeks.<BR>In the High group of SHR, the blood pressure did not increase over that of the Control after the rats reached 33 weeks of age.In the Low SHR group, the blood pressure was lower than those of the Control.At 33 weeks of age, the Low GK rats maintained a significantly lower blood pressure than the Control rats.The glucose, triglyceride, and TG /HDL values in the High SHR group were lower than those of the Control.In the High GK group, the triglyceride and TG/HDL levels were lower than those of the Control.In contrast, the TCho and HDL values in the High group significantly increased.Thus, our findings suggest that Tofu is effective in preventing hypertension, diabetes, and atherosclerosis development.Therefore Tofu is good healthy food and is to expected to prevent life-style related diseases.
- 日本食生活学会の論文
日本食生活学会 | 論文
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