Morphological study of age-related changes in the mandibular condyle of ICR mice
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概要
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Knowledge about age-related changes of the temporomandibular joint (TMJ) in ICR mice is of great interest for the understanding of histopathological alterations of the human TMJ. These changes are sometimes called degenerative or spontaneous osteoarthritic changes.However, there is a scarcity of information in the literature on morphologic changes due to normal age changes, in ICR male mice. The purpose of this investigation is to observe the age-related changes of ICR mice.As a result it was recognized that the main part of age changes was in the cartilaginous layer in articular surface of the condyle. The mesenchymal cell layer was thickened and the hypertrophic chondrocytes decreased and clustered. These findings were coincided with the changes in human condylar materials.
- 一般社団法人 日本顎関節学会の論文
一般社団法人 日本顎関節学会 | 論文
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