A case of ovarian carcinoid with massive ascites
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<B><I>Background</I>: </B>We report a rare case of ovarian insular carcinoid with massive ascites.<BR><B><I>Case</I>: </B>A 72-year-old woman reporting abdominal distension was diagnosed clinically with bilateral ovarian tumors with massive ascites based on USG and MRI. Tumor markers measured preoperatively were elevated, with CAl25 of 366.6U/m<I>l</I>, CA19-9 of 63.5 U/m<I>l</I>, SLX of 84 U/m<I>l</I> and CEA of 7.5 ng/m<I>l</I>. Laparotomy showed, a solid tumor originating from both ovaries with massive ascites, necessitating. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy. Pathologically, the right ovarian tumor was mature cystic teratoma and the left insular carcinoid. Cytological specimens of ascites showed that tumor cells with light-green stained granular cytoplasm, oval to round nuclei, and coarse granular chromatin were arranged in clusters or rosette-like formations. Immunohistochemically, tumor cells were positive for Grimelius, chromogranin A, NSE, AE-1, Serotonin, CD56, and CEA, but were negative for Peptide YY. Cytologically, cells were positive for chromogranin A.<BR><B><I>Conclusions</I>: </B>Typical cytological findings in ascites are, in addition to histological examination and immunohistochemistry, useful in diagnosing ovarian insular carcinoid.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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