A case of gastric marginal zone B-cell lymphoma with azurophilic granules.
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<B><I>Background</I>:</B> We report here on a case of primary gastric marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) with cytoplasmic azurophilic granules.<BR><B><I>Case</I>:</B> A 66-year-old man was admitted to the hospital with diarrhea and appetite loss. Endoscopic examination revealeda slightly elevated ulcerative tumor in the gastric fundus. Biopsy revealed MALT lymphoma, and partial gastrectomy was performed. The intraoperative cytology specimen was composed of numerous medium sized tumor cells with scatterd small lymphocytes and plasma cells. Papanicolaou staining showed the tumor cells had a moderate amount of clear cytoplasm, with indented nuclei enclosed in a thick nuclear menbrane, containing conspicuous nucleoli and finely dispersed chromatin. Giemsa stained specimens revealed coarse azurophilic granules in the mildly basophilic cytoplasm of approximately 21% of cells. Immunohistochemistry revealed the tumor cells were CD20cy (+), CD79a (+), CD3 (-), CD5 (-), CD10 (-), cCD23 (-) and Granzyme B (-).<BR><B><I>Conclusion</I>:</B> The findings in the present case suggest thatMALT lymphoma also exhibits intracytoplasmic azurophilic granules.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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