A study of endometrial cytology in benign cases. Differentiation from endometrial hyperplasia.:Differentiation. from endometrial hyperplasia

概要

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Objective: We evaluated cytological findings in benign cases to increase the accuracy of endometrial cytology for hyperplasia. Study Design: We selected 87 biopsied cases diagnosed as suspicious (possible hyperplasia). Histological findings were classified as benign in 31 (14 atrophic endometrium), 3 proliferative phase, 6 secretory phase, 5 irregular proliferation, polyp, and 56 hyperplasia (14 simple and 42 complex). Each case was compared for the appearance and frequency of abnormal clusters and of metaplastic epithelium. Results: 1) Appearance and frequency of dilated glands were high in hyperplasia, secretory phase, irregular proliferation, and polyp. 2) The appearance of clumps of irregularly ragged glands in atrophic endometrium and the proliferative phase was comparatively high. 3) The appearance and frequency of clumps with high densities of glands in benign were low. 4) In the appearance of metaplasia, no significance was between benign and hyperplasia Cases: Appearance of metaplasia were high in atrophic endometrium and the proliferative phase. Conclusion: The appearance and frequency of abnormal clusters and of metaplastic epithelium increased the diagnostic accuracy of hyperplasia in endometrial cytology.
特定非営利活動法人日本臨床細胞学会の論文