A case of enteropathy type intestinal T-cell lymphoma.
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概要
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<B><I>Background</I>:</B> Malignant lymphoma, Enteropathy type intestinal T-cell lymphoma (ETCL) is a rare primary intestinal disorder, paticularly in Japan. We report a case of ETCL arising in the duodenum.<BR><B><I>Case</I>:</B> A 51-year-old Japanese man presented with malabsorption syndrome, including hypoproteinemia. An ulcerating mass in the duodenum was resected. Intraoperative cytological specimens of the duodenal tumor contained numerous atypical medium to large lymphoid cells associated with a background of histiocytes. On Papanicolaou (Pap) stain, tumor cells had moderate amounts of amphophilic cytoplasm. Their nuclei were round or slightly indented, with a thick nuclear membrane, containing multiple small but conspicuous nucleoli situated at the nuclear membrane and finely dispersed chromatin. Scattered mitoses were also observed. Giemsa-stained specimens revealed numerous intracytoplasmic azurophilic granules. Based on histological examination of surgical materials, including immunohistochemical analysis, we confirmed ETCL.<BR><B><I>Conclusion</I>:</B> Giemsa-stained cytology specimens are informative when dealing with ETCL because azurophilic granules are easily identified in the cytoplasm of variable proportions of tumor cells. This feature, however, could not be determined in Pap-stained specimens.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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