Cytologic characteristics of well and poorly differentiated thyroid papillary carcinoma.
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概要
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<B><I>Objective</I>:</B> To assess the cytologic characteristics of poorly differentiated thyroid papillary carcinoma in aspiration cytology smears.<BR><B><I>Study Design</I>:</B> Aspiration cytology smears of 33 cases of thyroid papillary carcinoma, 16 well and 17 poorly differentiated, were assessed using the following criteria: 1) background, 2) total number of tumor cells, 3) appearance of cell clusters, and 4) characteristics of individual tumor cells.<BR><B><I>Results</I>:</B> Aspiration cytology findings for poorly differentiated thyroid papillary carcinoma were characterized as follows compared to well differentiated carcinoma: 1) presence of many tumor cells; 2) cell clusters with ill-defined, and irregular borders; 3) presence of many scattered tumor cells; 4) anisocytosis; 5) strong variation in nuclear/cytoplasmic ratio; and 6) variable sized nuclei and presence of oval nuclei.<BR><B><I>Conclusion</I>:</B> Aspiration cytology enable us to distinguish poorly differentiated thyroid papillary carcinoma from the well differentiated form based on cell cluster size and border, individual tumor cells size, and the presence of oval nuclei.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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