Role of morphometric analysis in cytological diagnosis of prostatic adenocarcinoma.
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概要
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<B><I>Objective</I>:</B> To investigate the role of morphometric analysis in cytological diagnosis of prostatic adenocarcinoma.<BR><B><I>Study Design:</I></B>The average nuclear diameters were measured in Papanicolaou-stained smears prepared from fine needle aspirates of ten patients belonging to each of the following four categories: benign lesions, well differentiated, moderately differentiated, and poorly differentiated adenocarcinoma. All cytological diagnoses were confirmed by histopathological studies of needle biopsies.<BR><B><I>Result:</I></B>The average nuclear diameter in each of these four groups was 10.6±1.8, 11. 3±1.6, 16.0±1.9, and 16.1±1.8 micrometers, respectively. There was no significant difference between the average nuclear diameter in benign lesions and in well-differentiated adenocarcinoma. The average nuclear diameter of moderately and poorly differentiated adenocarcinoma was significantly larger than in the other two categories.<BR><B><I>Conclusion</I>:</B> It is concluded that morphometric analysis of nuclei is of no value in cytological diagnosis of welldifferentiated adenocarcinoma, but that this method is a useful adjunct in cytological diagnosis of moderately and poorly differentiated adenocarcinoma.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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