Immunohistochemical study of binding pattern of endothelial cells in endometrial adenocarcinomas and hyperplasias.
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概要
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For the differential diagnosis of endometrial hyperplasia and well-differentiated adenocarcinoma, we detected endoth-elial, epithelial and stromal cells alone and in combination, using immnohistochemical methods, factor VIII and EMA.<BR>Seven cases of adenomatous hyperplasia, 3 of atypicalhyperplasia, 10 of well-differentiated adenocarcinoma, 10 of moderately differentiated adenocarcinorna, and 5 of poorly differentiated adenocarcinoma, which had been defined byhistological diagnosis, were examined in this study.<BR>As a result, factor VIII revealed that the cells which hadspindle shaped nuclei were endothelial cells.The bindingpatterns of endothelial and epithelial cells were observed in 9cases of well-differentiated adenocarcinoma, and suggestedthat the results were useful in discriminating adenomatous hyperplasia from well-differentiated adenocarcinoma.Theabove mentioned binding pattern was observed in one case ofatypical hyperplasia, but the significance of this result remains to be determined.<BR>The results of this study suggest that immunohisto-chemical methods are useful for identifying endometrial andepithelialcells.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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