A case report ectopic pituitary adenoma of the sphenoid sinus diagnosed only by fine needle aspiration cytology.
スポンサーリンク
概要
- 論文の詳細を見る
We report a case of prolactin-producing pituitary adenoma diagnosed by aspiration cytology from the sphenoid sinus.<BR>The patient was a 70-year-old woman with left exophthalmus and decreased visual acuity, who was admitted to the ophthalmology clinic. Imaging examination disclosed a tumor mass which showed destruction of the base of the sella turcica and invasion into the sphenoid sinus wall and left orbita. However, the pituitary gland itself was unremarkable.<BR>For conclusive diagnosis, aspiration cytology and biopsy of the tumor were performed from the sphenoid sinus. The biopsy revealed a proliferative tumor rich in vascular channels, but the histological diagnosis was not contributory due to markedly crushed tissue. Aspiration cytology revealed tumor cells that were 20-30 micron in size and presented small vacuoles in the nuclei and cytoplasm. The cytoplasm also had scatterd eosinophilic granules. Some cells showed domed projections at one end of the cytoplasm and crowded eosinophilic granules. Indented or distorted tumor cells were observed. Immunocytochemical staining using antiprolactin antibody revealed granular and/or diffuse, and localized collecting reactions in the cytoplasm.<BR>From the above cytological appearance, we considered the tumor to be a prolaction-producing pituitary adenoma. It was concluded to be ectopic by imaging.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
- Cytology of Carcinoid of Digestive Organs
- T-cell rich B-cell large cell lymphoma.
- Symposium on borderline lesions. 1. Aspiration cytology of lymph nodes with special reference to malignant lymphoma.
- A case of endometrioid adenocarcinoma, so-called secretory variant.
- Significant factors influencing the accuracy of PTCD bile cytology for bile duct lesions.