A case of the primary urethral malignant melanoma with an appearance of tumor cells in urine.
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We report a case of primary malignant melanoma of the male urethra. Primary malignant melanoma of the urinary tract is rare and accounts for less than 0.3% of all melanomas.<BR>A 64-year-old man was admitted to the hospital with dysuria and hematuria. An excretory urogram revealed a filling defect in the bulbous urethra.<BR>Tumor cells obtained from the urine appeared solitary and took on a sheet-like arrangement. Most of the tumor cells were round, and several tumor cells had irregularly shaped nuclei and prominent nucleoli. These cells were very similar to the malignat cells of transitional cell carcinoma, however, the cytoplasm of a few tumor cells was filled with fine granular melanin pigmentation.<BR>Immunostaining for S-100 protein and NSE (neuronspecific enolase) was positive. An electron micrograph showed numerous melanosomes in the cytoplasm.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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