Sputum cytology specimens judged to be suspicious.
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概要
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A total of 160 sputum cytology specimens were studied. Of these 109 specimens were from cases of cancer of the lung or adjacent organs, 34 were from cases of inflammatory disease diagnosed clinically, 7 were from cases of metaplasia diagnosed by biopsy specimens and there were 10 others. Of the 109 specimens from malignant disease, 82 cases had not been treated before.After reinvestigation, 49 were positive for malignancy, 11 were negative and the remainder were suspicious.The reasons why they were not judged as positive at first were mild cell atypia, few atypical cells and degeneration of the cells.In 27 specimens with lung cancer after treatment, 4 were judged as positive in cases with recurrence and 4 were negative.However, the remaining 19 specimens were judged as suspicious.In 41 specimens of inflammatory disease and metaplasia, 17 were compatible with a negative diagnosis and there were no specimens judged as positive.Hyperplasia of the bronchial epithelium must be distinguished from adenocarcinoma.In judging such cases as negative, an inflammatory background and atypical cells with cilia or the brush borders could be useful.<BR>In sputum cytology, detection of atypical cells is necessary for the early detection of malignancy.However, classification as "suspicious" is a problem for clinicians, because the actual meaning of "suspicious" is unclear.It is better to comment on the cytological findings and reasons for that judgement, and to indicate the subsequent steps to be taken, such as reexamination, follow-up or detailed examination. Clinicians should then decide based on the clinical findings.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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