Morphological study of Chlamydia-infection diseases. 2 Ultrastructural study of Chlamydia-infected cell of the human uterine cervix.:2. Ultrastructural study of Chlamydia-infected cell of the human uterine cervix
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Biopsy specimens from the uterine cervix were studied electron microscopically in 24 suspected cases of chlamydia infection. Chlamydia-infected cells were examined ultrastructually in two cases.<BR>(1) Cells with chlamydia were detected singly or in groups mainly in superficial and partly in intermediate layers of squamous metaplasia adjacent to the squamo-columnar junction.<BR>(2) Besides squamous metaplasia of columnar origin, chlamydial inclusion bodies were found in several types of columnar cells, including mucous-producing cells of cervical glands.<BR>(3) Chlamydial inclusion bodies were located in the cytoplasma adjacent to the nucleus, were round or slightly irregular in shape and 5-10μm in size, and differed in populations of elementary, intermediate and reticulate bodies according to the phase of infection.<BR>(4) Cellular changes by chlamydia infection were remarkable in nucleus and organella, though inclusion bodies and nuclear oppression were often encounted.<BR>(5) Many intracytoplasmic lumina were noted, requiring morphological differentiation from chlamydia inclusion bodies on a microscopic level.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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