Changes of Amyloid-invaded Intramucosal and Muscularis Mucosa Nerves in the Colon of Leprosy:Observation with Golgi Staining
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概要
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Amyloid-invaded intramucosal and musculasis mucosa nerves of the large intestines in two leprosy patients were studied with our modified Golgi Staining.The main findings were as follows; 1) Amyloid deposition was found in the mucosa and the mucosal muscle as well as on the small arterial walls. 2) Both nerve fibers passing through the muscle layer and vasomotor nerves in myenteric plexus were degenerated, coarsed and decreased in number. 3) And the circumnutated nerve fibers were disappeared and/or degenerated in amyloid-deposited arterial walls.With those findings, it might be possible to say that there are some lesions in sensory neurous at the mucosa of the colon with amyloid deposition.
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