Studies on Search for a Promising Immunopotentiative Substance for Treatment of Leprosy:(I) Analytical Studies on Bamboo Grass

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Since plant source polysaccharides were presumed to be immunopotentiative substances and suitable to the treatment of leprosy by their mild effect on host, at the first step, the analytical studies on the components of bamboo grass were performed. The results found were as follows1. Some extraction methods of bamboo grass were examined and compared.2. The monosaccharide components of acidic polysaccharides were equal to those found by Uchiyama, et al, using DEAE-cellulose column. However, the content of glucose was found to be highest in strongly acidic fraction and also presumed to be higher in lower molecular weight fractions. While, the contents of pentoses seemed to be contrary to the tendency of glucose content.3. Besides monosaccharides of carbohydrates, ribose and mannose were slightly detectable as free monosaccharides.4. The presence of small amount of conjugated sulfate could be presumed.5. Conjugated phosphate could not be detected.6. The amino acid composition of protein obtained by Sevag method was analyzed.7. Alkalies of bamboo grass were measured and a high content of potassium was noticed.
日本ハンセン病学会の論文