Influence of fluorescence brightening agents on yeast Saccharomyces cerevisiae.
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概要
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The influence of four types of fluorescence brightening agents (FBAs) on the yeast <I>Saccharomycs cerevisiae</I> in, as investigated. The FBAs used were derivatives of stilbene disulfonic acid disodium salt (FBA-1), coumarine (FBA-2), pyrazoline (FBA-3) and naphtylimide (FBA-4). FBA-1 inhibited the growth of yeast strongly, while FBA-2, -3 and -4 influenced the yeast only slightly. The growth inhibition of the yeast by each FBA can be correlated with the inhibition of sterol biosynthesis and with enzymes related to the electron-transport system in yeast. FBA-1 changed. the sterol composition by strongly accumulating the sterols found inthe early stages of biosyn- thesis and by strongly inhibiting the enzymes related to the electron-transport system. On the other hand, FBA-2, -3 and -4 did not have significant influence on either sterol biosynthesis or enzyme activity.
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