ショ糖投与ラットの血清,肝における脂質ならびにたん白質量の変動について

概要

論文の詳細を見る
In order to investigate the metabolic changes in rats fed high sucrose diet containing 8% of soybean oil, fourty male Wistar rats (initially weighing 80-90g) were divided into four groups and fed diets containing 0% (control), 10%, 20% and 50% of the calories from sucrose for 12 weeks. Total lipid and total cholesterol levels of serum were significantly increased in 10%, 20% and 50% sucrose diets. Increase in serum triglyceride level observed in sucrose-fed rats was significant in only 50% sucrose diet. There was, however, a tendency to decrease in serum NEFA of sucrose-fed rats, and the effect was significant in 50% sucrose diet. On the other hand, total liver lipid levels were significantly decreased both in 20% and 50% sucrose diets and liver triglyceride and total cholesterol levels were significantly decreased only in 50% sucrose diet. There were no significant changes of phospholipid levels both in serum and liver of sucrose-fed rats. Total protein contents in serum and liver were slightly increased in all sucrose diets. The increase of total protein content in sucrose-fed rats should be due to increase of globulin. Increase in α2-globulin fraction and change of electrophoretic pattern in β-globulin fraction were observed in 20% and 50% sucrose diets. Rats fed 10%, 20% and 50% sucrose diets had a higher serum amylase activity than rats fed starch only.
公益社団法人日本栄養・食糧学会の論文