Studies on Serum Enzymes in Cardiovascular Diseases with Special Reference to Serum Lactic Dehydrogenase Isoenzymes

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In the present investigation, the S-GOT, S-LDH, and LDH isoenzymes have been studied in a variety of cardiovascular diseases. As a result, it was found that the organ specificity revealed by the LDH isoenzyme pattern had considerably decreased, and it was confirmed that the serial determination and composite observation of the S-GOT, S-LDH, and LDH isoenzyme patterns reflect more specifically and sensitively the sites and grades of organ injury than does the single determination of the LDH isoenzyme pattern alone. Accordingly, it is suggested that the combined determination of certain appropriate enzymes and their isoenzyme patterns will be found important in future diagnostic enzymology.
社団法人日本循環器学会の論文