A Case of Renal Tubular Acidosis with an Abnormally High Plasma Renin Activity

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The activity of plasma renin was studied in a 45 year old male patient with renal tubular acidosis. The plasma renin activity, which was abnormally increased while plasma pH remained low, was decreased upon normalisation of plasma in response to treatment with alkalinizing salts. Abnormal renin secretion. in the present case may be explained by the damage of renal tubular cells leading to the disturbance of sodium balance at the site of JG apparatus.
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