A Nutritional Study of Anemia in Pregnancy:Changes in the Blood and Plasma Components of Anemic Women during Pregnancy (Part 2)

概要

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A reduction in hemoglobin occurs during normal pregnancy, this being quite evident in the third trimester of pregnancy. The cause of it is that the increase in the total red cell volume during pregnancy is proportionately less than the increase in plasma volume. This is the hemodilution and is not a true anemia. However, a few pregnant women showed a greater fall in hemoglobin concentration than could be reasonably attributed to hemodilution. Our previous report has suggested that anemia of Japanese pregnancies can be defined as the hemoglobin concentration below 10g/d<I>l</I> in the blood. In the present report a positive relationship between the hemoglobin level and the plasma iron in pregnancy was confirmed and the erythrocyte in anemic pregnancy was found to be of hypochromic type. Accordingly, the cause of anemia in these pregnancies was attributed to iron deficiency. The difficulties of the measurement of hemoglobin during pregnancy were also discussed in conjunction with the seasonal variations of hemoglobin concentration and plasma volume. The total concentration of plasma protein in anemic pregnancy fell more largely than that in normal pregnancy. Most of fall was due to a relatively large decline of serum albumin, and the globulin fractions showed the bigger differencies in anewic pregnancy from nonpregnant controls than that in normal pregnancy.
公益社団法人日本栄養・食糧学会の論文