A Canine Case of Primary Intra-Right Atrial Paraganglioma

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概要

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• An 11-year-old mixed breed dog was presented with signs of anorexia. Radiographic and ultrasound examination revealed a large mass in the heart, between the right atrium and the right ventricle. Upon gross inspection, a multilobulated tumor arising from the right atrial wall and occupying the right atrium was identified. Microscopical analysis demonstrated that this tumor consisted of neoplastic cells with granular cytoplasm, which were separated into nests by fine fibrovascular stroma, and was negative for Grimelius's method. Immunohistochemical examinations revealed that the neoplastic cells expressed chromogranin A, synaptophysin and neuron specific enolase. Electron microscopy revealed that the cytoplasm of the neoplastic cells held secretory granules. Based on these pathological findings, the tumor was diagnosed as a paraganglioma. This report is a rare case of primary paraganglioma deriving from the right atrium and provides a detailed characterization of its morphological features.

著者

• Park Chun-ho

  Laboratory Of Comparative Pathology Department Of Veterinary Clinical Sciences Graduate School Of Ve

• OYAMADA Toshifumi

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

• HATAI Hitoshi

  Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University

• TAODA Takahiro

  Laboratory of Small Animal Surgery 2, School of Veterinary Medicine, Kitasato University, Towada, Aomori, Japan

• YANAGAWA Hirotaka

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Towada, Aomori, Japan

• BOONSRIROJ Hassadin

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Towada, Aomori, Japan

• KIMITSUKI Kazunori

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Towada, Aomori, Japan

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• A Canine Case of Primary Intra-Right Atrial Paraganglioma

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