Spindle Cell Ameloblastic Carcinoma in a Labrador Retriever Dog

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概要

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• A 13-year-old castrated male Labrador retriever dog presented with a mass caudal to the first molar of his left mandible. Although the tumor was excised, a recurrent tumor was detected one month later and resected. Both tumors displayed invasive growth and were composed of neoplastic proliferation arranged in irregular lobules, nests and cords continuous with mucosal epithelium. The most prominent feature of the tumors was the presence of many proliferating spindle cells admixed with palisading basal-like cells, acanthocytes and stellate cells. In immunohistochemical examinations, the spindle cells were found to be positive for vimentin; cytokeratin AE1/AE3, 5/6, 14 and 19; and p63. The other neoplastic cells were positive for all of these markers shown above except vimentin. Based on these findings, the tumors were diagnosed as spindle cell ameloblastic carcinoma.

著者

• Park Chun-ho

  Laboratory Of Comparative Pathology Department Of Veterinary Clinical Sciences Graduate School Of Ve

• OYAMADA Toshifumi

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

• HATAI Hitoshi

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

• IBA Mitsuru

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

• KOJIMA Daisuke

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

• TSUCHIDA Yasuhiko

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

• HATAI Hitoshi

  Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University

• PARK Chun-Ho

  Laboratory of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan

関連論文

• Effects of ascorbic acid on proliferation and biological properties of bovine chondrocytes in alginate beads
• Spindle Cell Ameloblastic Carcinoma in a Labrador Retriever Dog
• Prevalence of Fowl Glioma-Inducing Virus in Chickens of Zoological Gardens in Japan and Nucleotide Variation in the env Gene
• A Canine Case of Primary Intra-Right Atrial Paraganglioma

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