Rifampicin-induced Acute Kidney Injury During the Initial Treatment for Pulmonary Tuberculosis: A Case Report and Literature Review
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概要
- 論文の詳細を見る
A 47-year-old man diagnosed with pulmonary tuberculosis was referred to our hospital. Rifampicin, isoniazid, pyrazinamide and ethambutol were administered, and the patient's symptoms promptly improved. On the 19th hospital day, he developed acute kidney injury with a fever and chills. Renal biopsy specimens indicated tubulointerstitial nephritis. Suspecting rifampicin-induced acute kidney injury, we discontinued the rifampicin and administered levofloxacin in its place. The patient's serum creatinine level subsequently gradually improved. We herein report this case and review eight cases reported in Japan. We found that the rifampicin toxicity appeared at both the initial administration and readministration. All eight patients presented with proteinuria.
- 社団法人 日本内科学会の論文
著者
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Inase Naohiko
Department Of Integrated Pulmonology Tokyo Medical And Dental University
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SAKASHITA Hiroyuki
Department of Internal Medicine, Bokuto Hospital
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Tsuchiya Kimitake
Department Of Integrated Pulmonology Tokyo Medical And Dental University Tokyo Japan
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Ito Eisaku
Department Of Clinical Pathology Graduate School Of Medicine Tokyo Medical And Dental University
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Chiba Sahoko
Department Of Respiratory Medicine Toride Kyodo General Hospital
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Sakashita Hiroyuki
Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan
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