Cytotoxic Activity of New Phenolic Compounds from Vietnamese Caesalpinia sappan

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概要

• 論文の詳細を見る

• Two new phenolic compounds, caesalpiniaphenols G–H (1 and 2), were isolated from Vietnamese Caesalpinia sappan heartwood. The chemical structures were established mainly by extensive spectroscopic studies and chemical evidence. Compounds 1 and 2 showed potent inhibitory activity against HL-60 cancer cell lines with respective IC50 values of 16.7 and 22.5 µg/mL. Treating HL-60 cells with various concentrations of 1 resulted in growth inhibition and the induction of apoptosis.

• 公益社団法人 日本農芸化学会の論文

著者

• Cuong To

  College of Pharmacy, Catholic University of Daegu

• Dang Nguyen

  Institute Of Ecology And Biological Resources Vietnam Academy Of Science And Technology

• Dat Nguyen

  Institute Of Marine Biochemistry Vietnam Academy Of Science And Technology

• HAI Nguyen

  Faculty of Chemistry, University of Science, Vietnam National University

• DAT Nguyen

  Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST)

• HUNG Tran

  Faculty of Chemistry, University of Science, Vietnam National University

• NHAN Nguyen

  Faculty of Chemistry, University of Science, Vietnam National University

• QUANG Ton

  Faculty of Chemistry, University of Science, Vietnam National University

• QUAN Tran

  Faculty of Chemistry, University of Science, Vietnam National University

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• Cytotoxic Activity of New Phenolic Compounds from Vietnamese Caesalpinia sappan

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