ナノDDSデバイスを用いた血管内治療の臨床応用 (特集 次世代治療を支えるDDS技術)
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概要
- 論文の詳細を見る
Drug eluting stent on the market at present is feared about serious side effects after use (Acute coronary syndrome caused by delayed thrombosis). It is suggested that delayed thrombosis comes from inflammatory reaction, fibrin deposition, and delayed re-endothelialization. We have already succeeded in the development of stent platform that has the function of Nano DDS using electro-deposition coating technology. In this review, we summarize the results of Pulse-Wave Infusion Catheter and statin nanoparticle eluting stent acquiring Proof of Concept by the porcine coronary-arteries models, with describing the outline of stent platform that has the function of Nano DDS.
- 日本DDS学会の論文
著者
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中野 覚
九州大学大学院 医学研究院循環器内科学
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江頭 健輔
九州大学大学院医学研究院
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江頭 健輔
九州大学大学院医学研究院・循環器病先端医療研究開発学
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由布 威雄
九州大学大学院医学研究院・循環器内科学
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