Periaortitis Associated with Anti-neutrophil Cytoplasmic Antibodies Induced by Bevacizumab Combination Therapy

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概要

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• Drug-induced vessel vasculitis is a rare complication of chemotherapy. In particular, few reports have investigated drug-induced large vessel vasculitis. We herein report the case of a 57-year-old woman with advanced lung adenocarcinoma who developed perinuclear anti-neutrophil cytoplastic antibodies (p-ANCA)-positive periaortitis induced by bevacizumab combination chemotherapy. With the increasing use of combination therapy with bevacizumab, the incidence of vascular complications will potentially increase. A noninfectious fever occurring during chemotherapy might be a sign of vasculitis; therefore, we must ensure that possible periaortitis is not overlooked.

• 社団法人 日本内科学会の論文

著者

• Oshita Fumihiro

  Department Of Internal Medicine National Cancer Center Hospital

• Kondo Tetsuro

  Department Of Physiology School Of Medicine Keio University

• Murakami Shuji

  Department Of Anatomy & Neurobiology Wakayama Medical University

• Ohe Miki

  Department Of Internal Medicine Division O

• Murakami Shuji

  Department of Thoracic Oncology, Kanagawa Cancer Center Hospital, Japan

• Saito Haruhiro

  Department of Thoracic Oncology, Kanagawa Cancer Center Hospital, Japan

• Yamada Kouzo

  Department of Thoracic Oncology, Kanagawa Cancer Center Hospital, Japan

• Saito Haruhiro

  Department of Respiratory Medicine, Yokohama City University School of Medicine, Japan

• Oshita Fumihiro

  Department of Thoracic Oncology, Kanagawa Cancer Center Hospital, Japan

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