Successful Treatment of Severe Newly Diagnosed Immune Thrombocytopenia Involving an Alveolar Hemorrhage with Combination Therapy Consisting of Romiplostim, Rituximab and Vincristine
スポンサーリンク
概要
- 論文の詳細を見る
A 51-year-old man was admitted due to a severe bleeding tendency. After he was diagnosed with immune thrombocytopenia (ITP), several therapies, including steroids, steroid pulse, vincristine and rituximab, were administered; however, the patient's bleeding symptoms were not sufficiently controllable with these treatments. Subsequently, a diffuse alveolar hemorrhage was observed. Treatment with a thrombopoietin receptor agonist, romiplostim, was initiated to prevent lethal hemorrhaging, although the efficacy of thrombopoietic receptor agonists in such emergency situations has not been elucidated. The initiation of romiplostim achieved prompt remission in platelets. This case suggests that combination therapy with romiplostim, rituximab and vincristine is effective in cases of newly diagnosed severe therapy-resistant ITP.
著者
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Takizawa Jun
Division of Hematology and Cardiology, Graduate School of Medical and Dental Science, Niigata Univer
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Toba Ken
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Sciences
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Okazuka Kiyoshi
Division Of Hematology Niigata University Graduate School Of Medical And Dental Sciences
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Masuko Masayoshi
Division Of Bone Marrow Transplantation Niigata University Medical And Dental Hospital
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Shibasaki Yasuhiko
Division Of Hematology Niigata University Graduate School Of Medical And Dental Sciences
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Furukawa Tatsuo
Division Of Bone Marrow Transplantation Niigata University Medical And Dental Hospital
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Tanaka Tomoyuki
Division Of Pathology Kinan General Hospital
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Moriyama Masato
Division Of Bone Marrow Transplantation Niigata University Medical And Dental Hospital
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Kobayashi Hironori
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Fuse Ichiro
Department of Transfusion Medicine, Niigata University Medical and Dental Hospital, Japan
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Takizawa Jun
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Matsuo Yuji
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Miyakoshi Shukuko
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Kozakai Takashi
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Fuse Kyoko
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Toba Ken
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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Furukawa Tatsuo
Division of Bone Marrow Transplantation, Niigata University Medical and Dental Hospital, Japan
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Okazuka Kiyoshi
Division of Hematology, Niigata Univerisity Medical and Dental Hospital, Japan
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